Remember, you can use the comparison and report card spreadsheets for an at-a-glance look at the features, benefits, and drawbacks of each tool. The comparison and report card spreadsheets are available in the Overview tab. In summary:
SalesForce: Free for 501(c)(3) organizations, but might require some additional advanced skill for setup.
QuickBase: Can easily import and export Microsoft Excel spreadsheets and create custom online forms. It has more than 250 standardized reports to help you get started quickly.
eTapestry: Has high security and is very easy to set up, but is not as flexible as the other tools to meet custom needs.